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Post by Walter on Mar 18, 2022 19:19:05 GMT -5
Thanks. From the study: "The binding affinity increased for Nirmatrelvir, MPro 13b, and Lopinavir (Fig 4), whereas no changes for Ivermectin, MPro N3, and GC-373. The lowest binding energy was found for Ivermectin against both wild and mutant main protease. The binding site for all drugs was similar, however, the interacted amino acids were different (Fig 5)." And then, later in the piece: "Through docking analysis, we revealed that the mutations in spike protein increased its binding affinity for its main receptor ACE2 while decreased binding affinity for its co-receptor NRP-1. All the promising drugs that target the main protease would also be effective against this variant; however, Ivermectin shows the strongest binding affinity, and Nirmatrelvir (Paxlovid), MPro 13b, and Lopinavir may be more effective against this variant. "I confess I have no idea what any of this means, but I did notice this at the top of the page: Important: e-prints posted on arXiv are not peer-reviewed by arXiv; they should not be relied upon without context to guide clinical practice or health-related behavior and should not be reported in news media as established information without consulting multiple experts in the field. As I've said, if Ivermectin can be shown to do a good job, let's sign it up and start using it. But until that occurs and some official body like the FDA signs off on it, IMO, it ain't ready for prime time. Dig deeper 151 ivermectin COVID-19 studies, 102 peer reviewed, 81 comparing treatment and control groups. Recently added:Lawrie Soto Efimenko Thairu Lim. Ivermectin has been officially adopted for early treatment in all or part of 22 countries (39 including non-government medical organizations). Submit updates/correction . c19ivermectin.com/Wonderful. When the USA approves it, I'll be right there to take it if needed. Until then, not so much. |
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Post by cbisbig on Mar 18, 2022 19:45:50 GMT -5
Dig deeper 151 ivermectin COVID-19 studies, 102 peer reviewed, 81 comparing treatment and control groups. Recently added:Lawrie Soto Efimenko Thairu Lim. Ivermectin has been officially adopted for early treatment in all or part of 22 countries (39 including non-government medical organizations). Submit updates/correction . c19ivermectin.com/Wonderful. When the USA approves it, I'll be right there to take it if needed. Until then, not so much. Suit yourself *shrug* |
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Post by DrSchadenfreude on Feb 7, 2023 19:01:05 GMT -5
Re-posting this JAMA study from 2022 for Horse Paste.
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Post by cbisbig on Feb 8, 2023 7:55:14 GMT -5
Re-posting this JAMA study from 2022 for Horse Paste. Re-posting that I've already provided numerous links from a number of studies and doctors to the contrary. Ivermectin works to prevent and eliminate covid, Fact! |
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Post by Walter on Feb 8, 2023 13:31:25 GMT -5
Re-posting this JAMA study from 2022 for Horse Paste. Re-posting that I've already provided numerous links from a number of studies and doctors to the contrary. Ivermectin works to prevent and eliminate covid, Fact! Why doesn't the FDA and the CDC agree with that idea? |
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Post by cbisbig on Feb 8, 2023 14:43:35 GMT -5
Re-posting that I've already provided numerous links from a number of studies and doctors to the contrary. Ivermectin works to prevent and eliminate covid, Fact! Why doesn't the FDA and the CDC agree with that idea? Because they can't make money from it |
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Post by Walter on Feb 8, 2023 16:35:25 GMT -5
Why doesn't the FDA and the CDC agree with that idea? Because they can't make money from it Does the FDA and CDC profit from drug sales? It would be good for the federal debt if they did, but alas, they do not. |
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Post by cbisbig on Feb 8, 2023 16:40:12 GMT -5
Because they can't make money from it Does the FDA and CDC profit from drug sales? It would be good for the federal debt if they did, but alas, they do not. big pharma does Everyone knows they're in cahoots with the fed |
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Post by Walter on Feb 8, 2023 17:26:30 GMT -5
Does the FDA and CDC profit from drug sales? It would be good for the federal debt if they did, but alas, they do not. big pharma does Everyone knows they're in cahoots with the fed Ah yes....there's that deep state conspiracy again. In other news...the sun seems to be heading for a sunset to the west of your current location. |
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Post by cbisbig on Feb 8, 2023 19:30:16 GMT -5
big pharma does Everyone knows they're in cahoots with the fed Ah yes....there's that deep state conspiracy again. Wow ! Seriously?! childrenshealthdefense.org/defender/big-pharma-lobbying-netted-big-contracts/Big Pharma’s Big Spending on Lobbying Netted Big Contracts in 2020 The record $306 million Big Pharma spent on lobbying last year paid off, according to Open Secrets, which said the federal government awarded lucrative contracts to pharma and medical device manufacturers. |
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Post by Panama pfRedd on Feb 8, 2023 20:18:50 GMT -5
Wasting your time on those clueless cucks, CB.
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................................  ................................ = Panama pfRedd - 2021 Regular Season Champion = ...............................  ................................
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Post by Walter on Feb 9, 2023 1:50:46 GMT -5
Ah yes....there's that deep state conspiracy again. Wow ! Seriously?! childrenshealthdefense.org/defender/big-pharma-lobbying-netted-big-contracts/Big Pharma’s Big Spending on Lobbying Netted Big Contracts in 2020 The record $306 million Big Pharma spent on lobbying last year paid off, according to Open Secrets, which said the federal government awarded lucrative contracts to pharma and medical device manufacturers. Hmmm...so you think lobbying Congress influences the FDA's drug approval process? |
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